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Transfer into the canaliculi is facilitated by the osmotic force generated by bile salt-dependent and bile salt-independent biliary flow (which is mediated by a chloride-bicarbonate exchanger, which pumps bicarbonate into bile)

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Am J Ther 25(2):e194e201 Sutcliffe TC et al (2017) Procyanidin B2 protects neurons from oxidative, nitrosative, and excitotoxic stress