Brief room temperature exposure is allowed during transport or shipping
Similarly, in microglia mitochondria, levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) have been shown to be regarded as a marker of DNA/ RNA oxidation due to the lack of protection of mitochondrial DNA (mtDNA) by histone proteins and its own limited repair capacity (41)
None of those claims have been evaluated in a large, controlled, randomized human trial
Category 2 preparations, made in ISO-classified cleanrooms with stricter environmental controls, can receive longer BUDs of up to 60 days refrigerated or even longer with stability testing data
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Every lot is independently tested for identity, purity, and content, with a lot-specific Certificate of Analysis available for review