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From its discovery in the Americas by indigenous natives to its global spread, tobacco has played a fundamental role in the history, economy, industry, and culture of many nations and regions across the globe

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Back to the Future Part II : In the alternate 1985 where Biff is a corrupt and powerful businessman, the museum dedicated to Biff's life has a "smoking required" sign at the entrance

As a result, tobacco users often develop long-term discoloration and an increased risk of gum disease

doi: 10.1016/0006-8993(93)90121-3 58 SariY.ToalstonJ