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10.1007/s11010-023-04850-9 104 WangC.-K.YangS.-C.HsuS.-C.ChangF

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

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European Patent Application EP2501823 (A1) Wang Z (2014) Whitening cosmetic and preparation method thereof

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RanGDP is converted to RanGTP by its chromatin-bound guanine exchange factor (GEF), Regulator of chromosome condensation 1 (RCC1) [8], while RanGAP1, present in the cytoplasm, catalyses the intrinsic GTPase activity of Ran, converting RanGTP to RanGDP [9, 10]