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This causes higher energy expenditure

10.1128/aem.69.8.4814-4822.2003 Appl

In women with significant menstrual losses, parenteral iron may be frequently necessary to keep up with ongoing losses

Compensatory effect of Selank on the mnestic functions disturbed by neurotoxic damage of the noradrenergic system of the rat brain

Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, et al

How B12 Deficiency Affects Your Metabolism and Energy Now, while B12 doesn't directly cause weight gain, a deficiency can certainly have an indirect impact on your body's energy levels and, consequently, your activity and metabolism