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Sex hormone balance, including estrogen, progesterone, and testosterone, is affected by the systemic inflammation and HPA axis dysregulation that mold exposure drives
In summary, brain-targeted sequence modification enhances the efficacy of treatment by increasing the brain delivery efficiency of drugs
Further, there is also a risk of secondary infections due to reduced immunity
For example, mesenchymal stem cell-derived cytokines have been shown to modulate astrocytic responses, with IL-6 preventing the progression of astrocyte reactivity following ischemic brain injury through the activation of the AMPKmTOR signaling pathway 145
2022ZDJS047)
