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In the absence of amino acids such as cystine, cells promote translation of ATF4 via the general control non-repressor 2 (GCN2) -eukaryotic initiation factor (eIF2a) signaling pathway, which promotes transcription of genes involved in amino acid metabolism and stress response, including SLC7A11, enabling cells to cope with amino acid starvation

BPC-157 is supplied for in vitro research use only

This means 0.125 mL (12.5 units on an insulin syringe) delivers 0.25 mg (250 mcg)

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Activation of these receptors by fluoxetine triggers several signalling cascades

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