Melatonin plays multi-functional roles including the regulation of circadian rhythms, immune modulation, oxidative processes, apoptosis, and mitochondrial homeostasis 655
As a result, the livers ability to produce the master antioxidant, glutathione, is reduced leading to oxidative damage, fatigue, and premature aging
Begin With a Lower Dosage Starting your supplement schedule with a lower dosage and working your way up to the recommended dosage may help you avoid any potential side effects of glutathione
Normally, antioxidants such as glutathione, catalase, and superoxide dismutase extinguish these sparks before they cause harm
Consult your doctor to determine whether NAC may benefit your health.
Both timings can work, but one is clearly more effective for most people