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Gudkov, p16(Ink4a) and senescence-associated -galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

This protective action likely involves regulating antioxidant gene expression via Nrf2 activation, diminishing excessive ROS accumulation, and reducing oxidative damage markers (e.g., 3-NT and 4-HNE), as evidenced by J Fan et al.s study on STZ-induced diabetic mouse wounds treated with PCs (Fan et al., 2021)

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Qiang et al

After its reconstituted, immediately refrigerate your HCG