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Trypsin (TPCK-treated, from bovine pancreas), pepsin (from porcine gastric mucosa), dithiothreitol (DTT), acetaminophen (APAP), HPLC-grade acetonitrile (ACN) and methanol (MeOH), iodoacetamide (IAM), glucose-6-phosphate dehydrogenase (type XV, from baker's yeast), and other chemicals were purchased from Sigma-Aldrich (St
Pharmacology of estrogens and progestogens: Influence of different routes of administration
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Hydroxyl radicals can oxidize membrane lipids and cause damage to keratinocytes and melanocytes in the epidermis
DNA samples obtained from patients enrolled by the Acute Liver Failure Study Group suggest the rs776746 polymorphism in CYP3A5 is associated with increased bioactivation of paracetamol via increased enzyme activity
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