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This decline correlates with the reduced regenerative capacity that comes with aging, which partly explains why shoulder injuries heal more slowly in older individuals

However, there is no FDA-approved indication for this use

You do not know what is in them

If for example there is a Candida overgrowth, your immune system may or may not be reacting to the situation the same as the next person

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Research is mixed, and supplementing with DHEA can be risky,7 but some studies suggest potential short-term, minor benefits (like improved feelings of well-being) in certain populations, such as older women with reduced natural DHEA levels.8 Ultimately, more research is needed before it can be said if DHEA supplementation is safe, particularly in the long term