The SMILES trial (Supporting the Modification of Lifestyle In Lowered Emotional States) was the first randomized controlled trial to investigate the efficacy of a 12-week dietary intervention in the treatment of major depressive disorder.23 Researchers designed a modified Mediterranean diet based on the Australian Dietary Guidelines and the Dietary Guidelines for Adults in Greece
[DOI] [PubMed] [Google Scholar] 19.Shaw AT, Kim DW, Nakagawa K, Seto T, Crino L, Ahn MJ, et al
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10.1038/nchembio.2261 44 DinalloV.MarafiniI.Di FuscoD.LaudisiF.FranzE.Di GraziaA.et al (2019)
