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The mucin secreted by the goblet cells forms a gel like mucus layer, which can absorb bacteria and toxins in the intestinal cavity and prevent them from directly contacting epithelial cells

In brief, a stepwise filtering approach was implemented in each subclass dataset [44]

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Triggers of elevated ceramide levels comprise hyperosmotic shock [122], secreted sphingomyelinases (SMases) during inflammation [125], sepsis [126] or severe coronavirus disease 2019 (COVID-19) [127], Clostridium perfringens epsilon toxin [128], and platelet-activating factor [129]

Comparative analysis of the distribution of segmented filamentous bacteria in humans, mice and chickens