In patients with progressive myoclonus epilepsy, a GSTT1 -null genotype has been associated with increased risk of developing the disease where it might contribute to enhanced susceptibility to oxidative stress 60
However, hepatic concentrations of AQ and DEAQ are likely higher as AQ strongly accumulates in the liver ( in vivo may be lower, exposure continues for a prolonged period as the half-life of DEAQ is 10 to 12 days (Krishna and White, 1996
Research shows glutathione supports antioxidant defenses, which may slow visible signs of aging, though it does not stop aging altogether What are the best natural ways to boost glutathione
[DOI] [PubMed] [Google Scholar] 41.Yurkova I
, 497 , 1117-1122, doi: Tili, E., Michaille, J
Conclusion: GSTA1 may be a good target for the discovery of innovative drug candidates as GSTA1 stabilizers or enhancers against MASLD