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It isn't about helping patients solve a problem

Unlike earlier broad-spectrum senolytics that can harm healthy tissue, FOXO4-DRI targets a molecular interaction unique to senescent cells

While E195R and R197E mutations reduced the biological activity of HGF to a certain level, the E159R mutation in HGF led to dramatically decreased phosphorylation of c-MET (Fig

Author contributions KPN: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing original draft, Writing review & editing

Considering that PSC activation is a key factor in pancreatic fibrosis, we speculated that excess ROS production induced by high glucose may induce PSC activation in vivo

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