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A predisposition towards women, a younger age group, and smaller nodule sizes in the affected gland have been clinically associated with HT and PTC

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light schedule: 12:12 h, light on at 7AM) with food and water available ad libitum unless stated otherwise

Mechanistically, hyperactivation of Drp1 suppresses hexokinase 1 (HK1), a glycolytic enzyme localized to the mitochondria, inducing metabolic reprogramming that promotes NLRP3-driven inflammation and oligodendrocyte pyroptosis (Pradeepkiran and Reddy, 2020

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