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350,351 When diseases advance, mitochondrial function deteriorates due to multiple factors, impairing the ability of mitochondria to generate ATP, increasing ROS production, and potentially enhancing mitochondrial membrane permeability, thus promoting inflammation and cell death

12.2.1 Potential synergistic effects In some preclinical studies, curcumin has shown the ability to enhance the efficacy of certain chemotherapeutic agents (e.g., paclitaxel, gemcitabine, cisplatin) by sensitizing cancer cells to the drugs, inhibiting drug resistance, and promoting apoptosis

WSAVA Liver Standardization Group eds

Rocha M, Apostolova N, Diaz-Rua R, Muntane J, Victor VM

Early ovarian ageing

European Neuropsychopharmacology , 48 , 331