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Who should avoid AHK-Cu Individuals with copper metabolism disorders, specifically Wilson disease or Menkes disease, should not use copper peptides without medical guidance

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Note on the tolerance/diminishing-effect claim: the widely repeated effect fades after 4 to 6 weeks figure appears as repeated online claims, not in any primary study I could locate

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These effects can include fatigue and weakness, numbness and tingling in the hands and feet, and memory loss and cognitive decline