[15] GHK-Cu has been shown to produce anti-inflammatory effects and stimulate release of growth factors such as brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF) and bone morphogenetic protein 2 (BMP-2)
In turn, sleep deprivation leads to an upregulation of proapoptotic and proinflammatory markers such as the apoptotic chromatin condensation inducer 1 (Acin1), heat shock protein family E member 1 (HSPE1), and golgin subfamily A member 3 (GOLGA3), thus indicating an overall beneficial function of sleep for myelins maintenance and turnover (Vivo and Bellesi, 2019)
Key Functions of B12: Energy Production: Helps convert food into energy by supporting carbohydrate metabolism
Arck et al ., also proposed the free radical theory of greying which described increased apoptosis, reduced oxidative stress protection and increased mitochondrial DNA damage in hair follicles leading to depletion of melanocytes and greying hair 60
ERGP likely plays a role in regulation of intracellular Ca 2+ levels in pancreatic -cells
These proteins, in turn, may induce apoptosis of old cells, thereby reducing the old cell burden in tissues
