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A similar PK profile was observed for inhibitor 2 (100 mg/kg i.p.), with 4.8, 3.9, and 3.0 M concentrations measured at 30, 60, and 120 min, respectively

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J Biol Chem 279: 5534155347 Kogan I, Ramjeesingh M, Li C, Kidd JF, Wang YC, Leslie EM, Cole SPC, Bear CE (2003) CFTR directly mediates nucleotideregulated glutathione flux

Accordingly, T2 B cells did not develop in Gclc -deficient hosts (Fig