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A cofactor is something that is required for an enzyme to catalyze a chemical reaction

Chronic heavy alcohol consumption can impair B12 status through poor dietary intake and malabsorption, though occasional alcohol is unlikely to significantly affect supplement absorption

Host & Pest Tips For Use Contraindications: This product is contraindicated for use unless cobalt deficiency is confirmed

Peters KM, Jaeger C, Killinger KA et al: Cystectomy for ulcerative interstitial cystitis: Sequelae and patients' perceptions of improvement

J Environ Chem Eng 4:287292

I also really like that they come in a glass bottle." To ensure quality, MegaFood Extra Strength Methyl B12 is third-party tested for pesticides, manufactured in NSF-certified facilities and tested for purity and potency by the company's ISO-certified labs