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For instance, the FXR agonist obeticholic acid (OCA) has been demonstrated to attenuate systemic inflammation by inhibiting the NF-B signaling pathway, while TGR5 activation similarly suppresses macrophage inflammatory responses 164,165,166

in other instances, from seconds up to several minutes

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Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice