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Trial registration Similar content being viewed by others Background Despite progress in global tobacco control [1], smoking remains one of the largest risk factors for disease globally [2] and a major cause of the gap in healthy life expectancy between the richest and poorest [3]

Looking forward, the market is forecast to reach USD 1.38 trillion by 2033, exhibiting a growth rate (CAGR) of 1.9% during 2025-2033

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