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These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)

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It was discovered way back in 1957 by Mills as a cytosolic enzyme from bovine erythrocytes [2]

Efficacy and safety of alirocumab in insulin-treated patients with type 1 or type 2 diabetes and high cardiovascular risk: rationale and design of the ODYSSEY DM-INSULIN trial

Most users start at a lower strength and step up as their skin acclimates

HCQ dose ranged from 100 to 500 mg daily