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1 DN is believed to be associated with neuronal, neuroglial cell and vascular endothelial cell injury caused by uncontrolled hyperglycemia, dyslipidemia and IR through multiple pathways, such as ERS, inflammation, oxidative stress and mitochondrial disorders

Acknowledgements This work was supported by the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre

J Appl Biol Biotechnol 8(3):8191

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