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This high hydrophilicity contributes to the low oral bioavailability of GSH, as it cannot cross the physical barriers of the gastrointestinal tract (GIT)
Conversely, the review also explores the potential of NAC as an antioxidant and a GSH-boosting agent, highlighting its capacity to cross the bloodbrain barrier and influence critical cysteine-containing proteins within the brain
This means that the enzyme wont be able to convert the testosterone to DHT
Typically, nanocarriers can protect medications from degradation, enhance drug absorption by facilitating epithelial permeation, alter pharmacokinetic distribution profiles, and promote intracellular uptake and distribution