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If NNMT inhibition both restores adipocyte energy expenditure (promoting fat reduction) and supports myogenic differentiation (preserving or enhancing muscle), the net body composition effect could be recomposition simultaneous fat loss and lean mass preservation

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The addition of glycine and vitamin B12 is intended to support patients experiencing issues such as fatigue, muscle loss, or neuropathycommon concerns during weight loss or diabetes treatmentand may offer metabolic, neurological, and musculoskeletal benefits

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[DOI] [PubMed] [Google Scholar] 36.Gao JG, Simon M