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Furthermore, we assumed that this effect was independent of p53, given that the plethora of models with different p53 statuses all show similar phenotypes

Where enhanced activity is observed, translational studies need to establish that enhanced activity is not counterproductive in terms of just increasing drug potency and its associated side effects, and hence no antitumour benefit

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And commitment

But if people are going to, what do you take

Dev Cell (2003) 4(4):4424