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Limitation: No preservative, so microbial contamination risk increases over time

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It can also create excessive foam and bubbles that trap peptide molecules and make dissolution uneven

Heart Lung Circ 2018;27:132734

Summary: In adults with overweight plus a complication or obesity without diabetes, once-weekly cagrilintide-semaglutide (CagriSema) produced substantially greater weight loss than placebo at 68 weeks

MO is capable of inducing a moderate inflammatory phase after injury, which is critical for the wound healing cascade, because it provides a suitable environment for the removal of harmful substances and tissue repair, prevents excessive leukocyte recruitment, and promotes the proliferation and migration of fibroblasts