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Menstrual cycle abnormalities in patients with prolactinoma and drug-induced hyperprolactinemia

Tirzepatide, an FDA-approved dual GIP/GLP-1 receptor agonist for type 2 diabetes and obesity, works through incretin-based glucose regulation and appetite suppression

doi: 10.1371/journal.pone.0162583 33 MacMillanELTamRZhaoYVavasourIMLiDKOgerJet al

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Scores on the Three-Factor Eating Questionnaire (TFEQ-R18) improved in all treatment groups, with Cagrilintide producing greater improvements than placebo in specific domains: cognitive restraint, notably at 1.2 mg and 4.5 mg, emotional eating notably at 0.3 mg and 2.4 mg, and uncontrolled eating notably at 1.24.5 mg