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Lancet 406 , 22572268 (2025)

TOPLINE: An analysis using molecular clock modeling of data from Barrett esophagus (BE) tissue samples revealed that the biological onset of BE occurred at a median age of approximately 29 years, which is more than 20 years before the recommended screening age of 50 years

The responsible agent is not known, but we have very recent evidence for presence of amyloid deposition and misfolded proteolipid protein in the brains of progressive MS patients supporting the proteopathic theory (Tsutsui et al., 2024)

People with a lower starting body mass index tended to lose the highest percentage, while those carrying more weight lost a larger absolute number of pounds even if the percentage read lower

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