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In the case of epitalon specifically, studies with standardized food consumption have yielded the same findings related to longevity

Back when companies could still offer B12 injection kits, they almost all used sterile water

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WARNINGS: Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

[3] It is contraindicated in uncontrolled hypertension and is not recommended for people with significant cardiovascular disease