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The heat causes the THCa molecules to lose their carboxylic group in the form of water vapor and CO2, effectively converting THCa into THC

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[5] Markets [edit] MS is mainly sold in Italy, but also is or was sold in Spain, France, Germany, Austria, Slovenia and Brazil

Extent of interaction and, by this, clinical relevance varies as some substrates are very sensitive to CYP 1A, e.g., duloxetine, others only moderately, e.g., clozapine, or weakly, e.g., valproate

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