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However, in the spontaneously hypertensive rat model, the expression of myostatin protein decreased in chronically hypertrophic myocardium and was significantly negatively correlated with left ventricular diastolic diameter/body weight ratio and left ventricular systolic diameter, but positively correlated with partial shortening of the middle wall (75)

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This may result in a shortage, producing a variety of health concerns such as fatigue, weakness, constipation, loss of appetite, and nerve-related issues

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