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The dissociation constant ( K D ) values for Cu(II) in NTS of HSA (Asp-Ala-His) and of bovine serum albumin (Asp-Thr-His), have been determined by a variety of methods such as potentiometric titration, equilibrium dialysis, ultrafiltration, isothermal titration calorimetry, Cu(II) electrode and several spectroscopic methods, including EPR 27

Increased opioid inhibition of GABA release in nucleus accumbens during morphine withdrawal

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It regulates cytokines (TNF-, IL-6), decreases swelling, and limits immune-cell overactivity