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10.1093/ije/dyw319 7 AxelssonA

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Importantly, increased levels of SOA and H 2 O 2 in both studies were associated with depletion of enzymatic antioxidants such as superoxide dismutase (SOD) catalase (CAT), glutathione reductase (GR) and glutathione peroxidase (GPx) as well as decreased expression of all examined antioxidant genes (GPx, GR, SOD and CAT) [8, 9]

Experimental vascular studies indicate that BPC-157 modulates endothelial nitric oxide synthase activity by altering the interaction between endothelial nitric oxide synthase and its regulatory binding partner caveolin-1 [1][2]

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