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Acting as a potent antioxidant, glutathione helps the body eliminate harmful toxins and free radicals, reducing the risk of cell damage
However, for the L-GSH group, there was a significant increase in the levels of reduced form of GSH in the RBCs at 3-months post L-GSH supplementation( Figure 4H )
Based on this, we hypothesized that OPA1 is a molecular target of TMQ0153
Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L , Reuben A, Heymach JV