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Beyond the phagocytic respiratory burst, G6PD acts more generally as a key regulator of cellular redox homeostasis and provides substrate for NADPH oxidase by generating NADPH, thus exerting an innate immune modulatory role in these capacities

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Furthermore, there were statistically significant increases in the number of UV-induced melanin deposits (spots) on both sides of the face in the placebo group

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The rise in 2,3-BPG lowers hemoglobins oxygen affinity, facilitating oxygen release