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Methods: In this prespecified imaging subanalysis of the PRESTIGE-AF trial, we centrally assessed brain CT and MRI scans taken before study enrolment from all included patients using established scales and definitions

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Patients know exactly what to do on day 1 and exactly what we are checking at day 90

Furthermore, probiotics help maintain immunological equilibrium by attenuating pathological inflammation through the inhibition of pro-inflammatory cytokine signaling and suppression of the nuclear factor-B (NF-B) pathway (253)

They are gentle exfoliators that digest surface proteins without strong acids