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Patients with pernicious anaemia or complete malabsorption typically require lifelong treatment at standard intervals, while those with partial malabsorption may have variable needs

For people with cobalt allergy (which is more common among people with nickel allergy) who are also at risk of vitamin B12 deficiency, the "general advice seems to be 'take just enough but not too much,' which isn't too different from dosing advice for all vitamins and drugs" (via ACSH)

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In some embodiments, the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof, is essentially in the form of micronized particles

None of these have been formally tested with retatrutide+cagrilintide

Owner-reported improvements in mobility and pain though objective measurements variable