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Biological plausibility exists but human evidence lacking

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Primary antibodies used in this study: MS4A15 (HMGU, N/A,1:10), ATP2A2 (Elabscience, E-AB-30196, 1:250), FLAG (Sigma, F7425, 1:2000), MYC (Abcam, ab206486, 1:2000), ERK1/2 (Cell Signaling, 4696, 1:1000), pERK1/2 (Cell Signaling, 9101, 1:1000), STAT3 (Cell Signaling, 9139, 1:1000), pSTAT3 (Cell Signaling, 4113,1:1000), AKT (Cell Signaling, 9272, 1:1000), pAKT (Cell Signaling, 9271,1:1000), -Actin (Cell Signaling, 3700, 1:2000), alpha-Tublin (Cell Signaling, 2125, 1:2000) and Vinculin (Abcam, ab130007, 1:500)

Barter PJ, Rye KA

doi: 10.1021/acs.chemrestox.2c00410

Some studies suggest that it may not be adequately absorbed by the digestive system, as the molecule can be broken down by stomach acids and enzymes before it reaches the bloodstream