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The hazardous properties of chemicals cannot be sufficiently determined using only non-animal methods therefore animal testing is still required to determine certain human health and environmental data

Thousands of explosions and fires One study published in 2018 estimated that more than 2,000 e-cigarette explosion and burn injuries sent users to US hospital emergency departments from 2015 to 2017

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Useful investigations would include: Composition of smoke from tobacco products other than cigarettes