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10.1093/stmcls/sxad010 Summary Keywords diabetic kidney disease (DKD), sodium-glucose co-transporter 2 inhibitors (SGLT2i), finerenone, gut-kidney axis, cardiorenal protection Citation Zhang H, Wang K, Zhao H, Qin B, Cai X, Wu M, Li J and Wang J (2025) Diabetic kidney disease: from pathogenesis to multimodal therapycurrent evidence and future directions

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We showed that our model accurately reproduces published clinical and experimental data on the dose-dependent time course of acetaminophen in the plasma, the accumulation of acetaminophen and its metabolites in the urine, and the depletion of glutathione caused by conjugation with the toxic product

The third group received normal saline concomitantly with Dox and served as the disease control