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We could talk about biological mechanisms all day, but if the compound being studied isn't what it claims to be, the entire conversation is moot
doi:10.1056/NEJMoa2301972 PubMed: This landmark study demonstrated 24.2% mean weight loss at 48 weeks with the 12mg dose in 338 adults with obesity, establishing retatrutide as the most effective obesity medication tested to date
Rapid weight loss, reduced appetite, and altered nutrient intake can negatively affect bone density a particular concern for women who already face hypoestrogenic states from certain endometriosis treatments
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Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome
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