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doi: 10.1016/j.ultsonch.2017.03.040 63

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The subsequent antigen presentation triggers the activation of Th1 and Th17 cells, leading to the release of pro-inflammatory cytokines (IL-2, TNF-, IFN-, IL-17), which in turn amplify oxidative stress and perpetuate an amplifying loop of inflammation and tissue damage (Kubiak et al

Antonopoulos DA, Aminov RI, Duncan PA, White BA, Mackie RI: Characterization of the gene encoding glutamate dehydrogenase (gdhA) from the ruminal bacterium Ruminococcus flavefaciens FD-1

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A lot of them describe adverse effects such as nausea or dizziness, but attribute them to detox symptoms