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In many conditions of metabolic stress, the genes that convert NR to NAD are up-regulated, which provides unique value over all other NAD precursors." "With the clear preclinical benefits of NR observed in the brains of mice, I look forward to future clinical trial findings from testing in human subjects

Zhou 2014)

Folic acid, by contrast, must be convertedif thats blocked, unmetabolized folic acid (UMFA) can build up, which may carry risks

Typical dosing range: 250-500 mcg subcutaneously per day, with clinical trials using up to 1 mg daily

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