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Elevates NAD+ and S-adenosylmethionine (SAM) levels, shifting metabolic flux toward energy expenditure and away from fat storage 1-4

Preclinical work in obese murine models suggests that encapsulated 5-Amino-1MQ administration led to decreases in overall body weight and reductions in white adipose mass

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When NNMT is overactive, it consumes S-adenosylmethionine (SAM) and reduces levels of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme involved in cellular energy production

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