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repletion reverses hematologic symptoms within days and neurologic sequelae over weeks, reflecting differential tissue turnover

A concern would be the development of FLD, since liver specific PNPLA2 KO mice develop FLD

Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

Nerve damage