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10.1172/JCI164199 83

Kroemer, Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol

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Methodology Data source: HealthTech Alpha by Galen Growth, Q2 2026 , covering data up to 15 April 2026

Although Drp1-Ser637 phosphorylation predominantly suppresses mitochondrial fission under most physiological conditions, emerging evidence indicates its biological functions exhibit cell type-specific dependency and are dynamically regulated by microenvironmental signaling cues and upstream regulatory networks (Serasinghe and Chipuk, 2017)

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