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Discontinue use and seek professional advice if significant irritation or an allergic reaction occurs

Future studies will need to examine long-term safety, effects in female mice, tissue-specific responses, optimal dosing, and possible off-target effects

Chen X, Yu C, Kang R, Tang D

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The two are not interchangeable: bacteriostatic water has no electrolytes

Furthermore, treatment with rhein has effectively reversed alterations in Klotho and TLR4, thereby reducing inflammatory responses ( 2.4.2 Emodin Rheum palmatum is a commonly used herb in TCM for the treatment of AKI